Nucleotide Sequence and Chromosomal Mapping of the Human c‐yes‐2 Gene

Kentaro Semba*, Makoto Nishizawa, Hitoshi Satoh, Shin‐ichi ‐i Fukushige, Michihiro C. Yoshida, Motomichi Sasaki, Ken‐ichi ‐i Marsusbra, Tadashi Yamamoto, Kumao Toyoshima

*この研究の対応する著者

研究成果査読

8 被引用数 (Scopus)

抄録

We molecularly characterized the second gene, c‐yes‐2, of two copies of yes‐related genes which we previously found to contain in the human genome. First, nucleotide sequence analysis revealed that the c‐yes‐2 gene is a pseudogene of the c‐yes‐1 gene. Second, by using two independent methods, hybridization of both DNAs from sorted chromosomes and metaphase spreads with c‐yes‐2 DNA, we assigned the c‐yes‐2 gene to chromosome 22q11.2. This chromosomal localization is inconsistent with that given in our previous report. The failure of proper mapping in our experiment might have been caused by instability of hybrid cell clones.

本文言語English
ページ(範囲)710-717
ページ数8
ジャーナルJapanese Journal of Cancer Research
79
6
DOI
出版ステータスPublished - 1988 6
外部発表はい

ASJC Scopus subject areas

  • 腫瘍学
  • 癌研究

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