One-Pot Fabrication of Dendritic NiO@carbon-nitrogen Dot Electrodes for Screening Blood Glucose Level in Diabetes

Naeem Akhtar, Sherif A. El-Safty*, Mamdouh E. Abdelsalam, Hiroshi Kawarada

*この研究の対応する著者

研究成果: Article査読

44 被引用数 (Scopus)

抄録

Selective and sensitive glucose sensors with fast response for screening diabetic blood level are demanded. In this paper, the one-pot nanoarchitecture of dendritic NiO@carbon-nitrogen (C-N) dots (designated as NCD) sphere-wrapping Ni foam electrodes are reported as an effective and sensitive glucose sensor in blood samples. In this construction design, the NCD sphere electrode with excessive surface defects, large fractions of catalytic active sites, high surface area, and mobility of electron transfer through the actively surface NCD sphere can massively enhance the electrocatalytic activity for nonenzymatic glucose detection in diabetic blood. This portable sensor enables highly sensitive recognition of glucose detection (≈0.01 × 10-6m) over a wider linear range (≈0.005-12 × 10-3m) with rapid response time of a few seconds. The key result is that the engineered NCD sphere electrodes function as simple, easy-to-use electrochemical sensing assays of glucose levels in diabetic blood patients with a wide range of precision or linearity, recyclability, and excellent selectivity, even in the presence of potentially interfering organic (ascorbic acid, uric acid, dopamine, lactose, maltose, and sucrose) and inorganic (NaCl, Na2SO4, KCl, and K2SO4) species. The results demonstrate the potential for the electrochemical sensors to be used in preventing serious health problems associated with diabetes mismanagement.

本文言語English
ページ(範囲)2110-2119
ページ数10
ジャーナルAdvanced Healthcare Materials
4
14
DOI
出版ステータスPublished - 2015 10月 7

ASJC Scopus subject areas

  • 生体材料
  • 生体医工学
  • 薬科学

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