Optical trapping techniques in bioanalysis

Kenji Yasuda*

*この研究の対応する著者

研究成果: Chapter

抄録

Knowledge of life has expanded dramatically during the twentieth century and has produced the modern disciplines of genomics and proteomics. However, there remains the great challenge of discovering the integration and regulation of these living components in time and space within the cell. As we move into the postgenomic period, the complementarity between genomics and proteomics will become apparent, and the connections between them will be exploited, although, neither genomics, proteomics, nor, for that matter, their simple combination will provide the data necessary to interconnect molecular events in living cells in time and space. e cells in a group are dierent entities. Each of them respond to the perturbations dierently (Spudich and Koshland 1976). e dierences between cells arise even among those grown in homogeneous conditions and considered to have identical genetic information. Why and how do these dierences arise? ey might be caused by several factors like unequal distributions of biomolecules in cells, mutations, interactions between cells, and uctuations of environmental elements. A system that can observe interactions between specic cells continuously under fully controlled.

本文言語English
ホスト出版物のタイトルBiomedical Photonics Handbook, Second Edition
ホスト出版物のサブタイトルTherapeutics and Advanced Biophotonics
出版社CRC Press
ページ457-491
ページ数35
ISBN(電子版)9781420085174
ISBN(印刷版)9781420085167
DOI
出版ステータスPublished - 2014 1月 1
外部発表はい

ASJC Scopus subject areas

  • 医学(全般)
  • 生化学、遺伝学、分子生物学(全般)
  • 物理学および天文学(全般)
  • 工学(全般)

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