Palladium-catalyzed 5-exo-selective reductive Mizoroki-Heck reaction of aryl chlorides with 2,5-norbornadiene

Fuyuki Aida, Hisashi Sone, Ryuhei Ogawa, Takeharu Hamaoka, Isao Shimizu

研究成果: Article査読

6 被引用数 (Scopus)

抄録

5-exo-Selective reductive Mizoroki-Heck reaction of 4-tert-butyl-1-chlorobenzene with 2,5-norbornadiene has been achieved by [PdCl<inf>2</inf>(PCy<inf>3</inf>)<inf>2</inf>]/HCO<inf>2</inf>Na to give 5-exo-(4-tertbutylphenyl)-2-norbornene in 95% yield. When Cs<inf>2</inf>CO<inf>3</inf> is used as a base in the absence of a reducing reagent, an exo-benzocyclobutene-fused norbornene, 6-tert-butyl-1,4,4a,8b-tetrahydro-1,4-methanobiphenylene is produced in 62% yield.

本文言語English
ページ(範囲)715-717
ページ数3
ジャーナルChemistry Letters
44
5
DOI
出版ステータスPublished - 2015

ASJC Scopus subject areas

  • 化学 (全般)

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