Panic disorder and locomotor activity

Noriyuki Sakamoto, Kazuhiro Yoshiuchi*, Hiroe Kikuchi, Yoshiyuki Takimoto, Hisanobu Kaiya, Hiroaki Kumano, Yoshiharu Yamamoto, Akira Akabayashi

*この研究の対応する著者

研究成果: Article査読

15 被引用数 (Scopus)

抄録

Background: Panic disorder is one of the anxiety disorders, and anxiety is associated with some locomotor activity changes such as "restlessness". However, there have been few studies on locomotor activity in panic disorder using actigraphy, although many studies on other psychiatric disorders have been reported using actigraphy. Therefore, the aim of the present study was to investigate the relationship between panic disorder and locomotor activity pattern using a wrist-worn activity monitor. In addition, an ecological momentary assessment technique was used to record panic attacks in natural settings. Methods: Sixteen patients with panic disorder were asked to wear a watch-type computer as an electronic diary for recording panic attacks for two weeks. In addition, locomotor activity was measured and recorded continuously in an accelerometer equipped in the watch-type computer. Locomotor activity data were analyzed using double cosinor analysis to calculate mesor and the amplitude and acrophase of each of the circadian rhythm and 12-hour harmonic component. Correlations between panic disorder symptoms and locomotor activity were investigated. Results: There were significant positive correlations between the frequency of panic attacks and mesor calculated from double cosinor analysis of locomotor activity (r = 0.55) and between HAM-A scores and mesor calculated from double cosinor analysis of locomotor activity (r = 0.62). Conclusion: Panic disorder patients with more panic attacks and more anxiety have greater objectively assessed locomotor activity, which may reflect the "restlessness" of anxiety disorders.

本文言語English
論文番号23
ジャーナルBioPsychoSocial Medicine
2
DOI
出版ステータスPublished - 2008 11月 18
外部発表はい

ASJC Scopus subject areas

  • 社会心理学
  • 心理学(全般)
  • 精神医学および精神衛生
  • 生物学的精神医学

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