抄録
We present a novel peptide-based ligand screening system for G protein-coupled receptors (GPCRs) in water-in-oil (W/O) microdroplets. This system is an in vitro gene screening system for peptides that activate a target GPCR expressed in yeast. We show that the system is applicable to human GPCRs. This system will be a powerful tool for identifying novel peptide ligands for liganded mammalian GPCRs and orphan mammalian GPCRs.
本文言語 | English |
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ホスト出版物のタイトル | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 |
出版社 | Chemical and Biological Microsystems Society |
ページ | 965-967 |
ページ数 | 3 |
ISBN(印刷版) | 9780979806476 |
出版ステータス | Published - 2014 |
イベント | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States 継続期間: 2014 10月 26 → 2014 10月 30 |
Other
Other | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 |
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国/地域 | United States |
City | San Antonio |
Period | 14/10/26 → 14/10/30 |
ASJC Scopus subject areas
- 制御およびシステム工学