PGLN: A newly identified amino phosphoglycolipid species in Thermus thermophilus HB8

Naoki Nemoto*, Masahiko Kawaguchi, Kei Yura, Haruo Shimada, Yoshitaka Bessho

*この研究の対応する著者

研究成果: Article査読

抄録

Thermus thermophilus has several minor lipid molecules with structures that have not been described yet. In this study, we identified a new lipid molecule in T. thermophilus HB8 with an amino group at the polar head, by detecting lipid spots with HPTLC and mass spectrometry. The structure of the lipid resembles an amino sugar phospholipid, except for the glucosamine that lacks an acetyl group. We named this amino phosphoglycolipid PGLN, and proposed its synthetic pathway from a precursor, phosphatidyl-glyceric alkylamine. The primary amine structure of PGLN may contribute to high temperature adaptation through electrostatic interactions between the head groups.

本文言語English
論文番号101377
ジャーナルBiochemistry and Biophysics Reports
32
DOI
出版ステータスPublished - 2022 12月

ASJC Scopus subject areas

  • 生物理学
  • 生化学

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