Polyadenylation in mammalian mitochondria: Insights from recent studies

Takashi Nagaike, Tsutomu Suzuki, Takuya Ueda

研究成果: Review article

30 引用 (Scopus)

抜粋

Polyadenylation in animal mitochondria is very unique. Unlike other systems, polyadenylation is needed to generate UAA stop codons that are not encoded in mitochondrial (mt) DNA. In some cases, polyadenylation is required for the mt tRNA maturation by editing of its 3′ termini. Furthermore, recent studies on human mt poly(A) polymerase (PAP) and PNPase provide new insights and questions for the regulatory mechanism and functional role of polyadenylation in human mitochondria.

元の言語English
ページ(範囲)266-269
ページ数4
ジャーナルBiochimica et Biophysica Acta - Gene Regulatory Mechanisms
1779
発行部数4
DOI
出版物ステータスPublished - 2008 4 1
外部発表Yes

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics

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