Polyadenylation in mammalian mitochondria: Insights from recent studies

Takashi Nagaike, Tsutomu Suzuki, Takuya Ueda

研究成果: Review article査読

31 被引用数 (Scopus)

抄録

Polyadenylation in animal mitochondria is very unique. Unlike other systems, polyadenylation is needed to generate UAA stop codons that are not encoded in mitochondrial (mt) DNA. In some cases, polyadenylation is required for the mt tRNA maturation by editing of its 3′ termini. Furthermore, recent studies on human mt poly(A) polymerase (PAP) and PNPase provide new insights and questions for the regulatory mechanism and functional role of polyadenylation in human mitochondria.

本文言語English
ページ(範囲)266-269
ページ数4
ジャーナルBiochimica et Biophysica Acta - Gene Regulatory Mechanisms
1779
4
DOI
出版ステータスPublished - 2008 4
外部発表はい

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics

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