Polyadenylation in mammalian mitochondria: Insights from recent studies

Takashi Nagaike, Tsutomu Suzuki, Takuya Ueda

研究成果: Review article

29 引用 (Scopus)

抄録

Polyadenylation in animal mitochondria is very unique. Unlike other systems, polyadenylation is needed to generate UAA stop codons that are not encoded in mitochondrial (mt) DNA. In some cases, polyadenylation is required for the mt tRNA maturation by editing of its 3′ termini. Furthermore, recent studies on human mt poly(A) polymerase (PAP) and PNPase provide new insights and questions for the regulatory mechanism and functional role of polyadenylation in human mitochondria.

元の言語English
ページ(範囲)266-269
ページ数4
ジャーナルBiochimica et Biophysica Acta - Gene Regulatory Mechanisms
1779
発行部数4
DOI
出版物ステータスPublished - 2008 4 1
外部発表Yes

Fingerprint

Polyadenylation
Mitochondria
Polynucleotide Adenylyltransferase
Transfer RNA
Mitochondrial DNA
Animals
Terminator Codon

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Genetics
  • Structural Biology

これを引用

Polyadenylation in mammalian mitochondria : Insights from recent studies. / Nagaike, Takashi; Suzuki, Tsutomu; Ueda, Takuya.

:: Biochimica et Biophysica Acta - Gene Regulatory Mechanisms, 巻 1779, 番号 4, 01.04.2008, p. 266-269.

研究成果: Review article

Nagaike, Takashi ; Suzuki, Tsutomu ; Ueda, Takuya. / Polyadenylation in mammalian mitochondria : Insights from recent studies. :: Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 2008 ; 巻 1779, 番号 4. pp. 266-269.
@article{967dba6654bf4d28982be593815af7ae,
title = "Polyadenylation in mammalian mitochondria: Insights from recent studies",
abstract = "Polyadenylation in animal mitochondria is very unique. Unlike other systems, polyadenylation is needed to generate UAA stop codons that are not encoded in mitochondrial (mt) DNA. In some cases, polyadenylation is required for the mt tRNA maturation by editing of its 3′ termini. Furthermore, recent studies on human mt poly(A) polymerase (PAP) and PNPase provide new insights and questions for the regulatory mechanism and functional role of polyadenylation in human mitochondria.",
keywords = "Mitochondrial, mRNA stability, Poly(A) polymerase, Polyadenylation",
author = "Takashi Nagaike and Tsutomu Suzuki and Takuya Ueda",
year = "2008",
month = "4",
day = "1",
doi = "10.1016/j.bbagrm.2008.02.001",
language = "English",
volume = "1779",
pages = "266--269",
journal = "Biochimica et Biophysica Acta - Gene Regulatory Mechanisms",
issn = "1874-9399",
publisher = "Elsevier",
number = "4",

}

TY - JOUR

T1 - Polyadenylation in mammalian mitochondria

T2 - Insights from recent studies

AU - Nagaike, Takashi

AU - Suzuki, Tsutomu

AU - Ueda, Takuya

PY - 2008/4/1

Y1 - 2008/4/1

N2 - Polyadenylation in animal mitochondria is very unique. Unlike other systems, polyadenylation is needed to generate UAA stop codons that are not encoded in mitochondrial (mt) DNA. In some cases, polyadenylation is required for the mt tRNA maturation by editing of its 3′ termini. Furthermore, recent studies on human mt poly(A) polymerase (PAP) and PNPase provide new insights and questions for the regulatory mechanism and functional role of polyadenylation in human mitochondria.

AB - Polyadenylation in animal mitochondria is very unique. Unlike other systems, polyadenylation is needed to generate UAA stop codons that are not encoded in mitochondrial (mt) DNA. In some cases, polyadenylation is required for the mt tRNA maturation by editing of its 3′ termini. Furthermore, recent studies on human mt poly(A) polymerase (PAP) and PNPase provide new insights and questions for the regulatory mechanism and functional role of polyadenylation in human mitochondria.

KW - Mitochondrial

KW - mRNA stability

KW - Poly(A) polymerase

KW - Polyadenylation

UR - http://www.scopus.com/inward/record.url?scp=41549094036&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=41549094036&partnerID=8YFLogxK

U2 - 10.1016/j.bbagrm.2008.02.001

DO - 10.1016/j.bbagrm.2008.02.001

M3 - Review article

C2 - 18312863

AN - SCOPUS:41549094036

VL - 1779

SP - 266

EP - 269

JO - Biochimica et Biophysica Acta - Gene Regulatory Mechanisms

JF - Biochimica et Biophysica Acta - Gene Regulatory Mechanisms

SN - 1874-9399

IS - 4

ER -