Potential improvement in rehabilitation quality of 2019 novel coronavirus by isometric training system; is there “muscle-lung cross-talk”?

Hadi Nobari, Mohamad Fashi, Arezoo Eskandari, Jorge Pérez-Gómez, Katsuhiko Suzuki

研究成果: Article査読

1 被引用数 (Scopus)

抄録

The novel Coronavirus Disease 2019 (COVID-19) crisis is now present in more than 200 countries. It started in December 2019 and has, so far, led to more than 149, 470,968 cases, 3,152,121 deaths, and 127,133,013 survivors recovered by 28 April 2021. COVID-19 has a high morbidity, and mortality of 2%, on average, whereas most people are treated after a period of time. Some people who recover from COVID-19 are left with 20 to 30% decreased lung function. In this context, exercise focused on skeletal muscle with minimal lung involvement could potentially play an important role. Regular exercise protects against diseases associated with chronic low-grade systemic inflam-mation. This long-term effect of exercise may be ascribed to the anti-inflammatory response elicited by an acute bout of exercise, which is partly mediated by muscle-derived myokines. The isometric training system seems to have this feature, because this system is involved with the skeletal muscle as the target tissue. However, no studies have examined the effect of exercise on the treatment and recovery of COVID-19, and, more importantly, “muscle–lung cross-talk” as a mechanism for COVID-19 treatment. It is suggested that this theoretical construct be examined by researchers.

本文言語English
論文番号6304
ジャーナルInternational journal of environmental research and public health
18
12
DOI
出版ステータスPublished - 2021 6 2

ASJC Scopus subject areas

  • 汚染
  • 公衆衛生学、環境および労働衛生
  • 健康、毒物学および変異誘発

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