Precise detection of singly mismatched DNA with functionalized diamond electrolyte solution gate FET.

Shoma Kuga, Shinya Tajima, Jung Hoon Yang, Kazuyuki Hirama, Hiroshi Kawarada

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

The DC operation of diamond electrolyte solution gate FETs (SGFETs) and discrimination of complementary and singly mismatched DNAs in solution were demonstrated. The transconductance (gm), which is the sensitivity for detecting the hybridization of DNA on SGFET, was increased from 60 μS/mm to 9.5 mS/mm by miniaturization of FET. Hybridization of target DNA with probe DNA was detected by the gate potential shift caused by the negative charges on DNA immobilized on the channel surface. The change in gate potential caused by the hybridization of complementary DNA was about 25 mV. The ratio of change in gate potential by hybridization of complementary and single-mismatched DNA was 3:1 on diamond SGFET.

本文言語English
ホスト出版物のタイトル2008 IEEE International Electron Devices Meeting, IEDM 2008
DOI
出版ステータスPublished - 2008 12 1
イベント2008 IEEE International Electron Devices Meeting, IEDM 2008 - San Francisco, CA, United States
継続期間: 2008 12 152008 12 17

出版物シリーズ

名前Technical Digest - International Electron Devices Meeting, IEDM
ISSN(印刷版)0163-1918

Conference

Conference2008 IEEE International Electron Devices Meeting, IEDM 2008
CountryUnited States
CitySan Francisco, CA
Period08/12/1508/12/17

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Electrical and Electronic Engineering
  • Materials Chemistry

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