Prediction of the carbonmonoxyhemoglobin levels during and after carbon monoxide exposures in various animal species

I. Tyuma, Y. Ueda, K. Imaizumi, H. Kosaka

研究成果: Article査読

32 被引用数 (Scopus)

抄録

The equation derived by Coburn, Forster, and Kane (1965) for the absorption and elimination processes of carbon monoxide was solved analytically with less-restrictive assumptions. The solution can predict the COHb levels during and after exposures of 50 to 500 ppm CO not only in human subjects but also in rats and mice with reasonable accuracy, except for the CO elimination by breathing hyperbaric oxygen. Physiological parameters required for the prediction are only body mass and hemoglobin concentration. It has been shown that the rate of both processes is inversely proportional to B(0,24) in mammals, where B is the body mass: the smaller the animal, the faster the rate of both absorption and elimination.

本文言語English
ページ(範囲)131-143
ページ数13
ジャーナルJapanese Journal of Physiology
31
2
出版ステータスPublished - 1981
外部発表はい

ASJC Scopus subject areas

  • Physiology

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