Preparation of biocompatible hydrogels reinforced by different nanosheets

Taiga Ito, Saki Endo, Yoshiyuki Sugahara, Ryota Tamate, Régis Guégan*

*この研究の対応する著者

研究成果: Article査読

抄録

The impact of inorganic nanosheets with various chemical compositions and properties at different concentrations on the rheological properties and the gelation formation of a thermo-responsive hydrogel was investigated. F127 Pluronic triblock copolymers, with the structure (EO)99(PO)65(EO)99 (EO: ethylene oxide and PO propylene oxide respectively), functionalized by dimethacrylate (F127-DMA) at a concentration of 25% was used in this study. After careful characterization by complementary techniques: transmission electron microscopy (TEM), atomic force microscopy (AFM), and X-ray diffraction of nanosheets derived from the peeling of layered materials (montmorillonite, organoclays and hexaniobate), the nanosheets were seen to be suitably dispersed in the hydrogels. The inclusion of hydrophobic nanosheets (i.e. those treated with the grafting of surfactants onto their surface: organoclays and hexaniobate) leads to a depression of the gelation temperature while the nanocomposites exhibit an enhancement of their elastic properties, as determined by rheological measurements. In contrast, the inclusion of hydrophilic nanosheet derived from raw montmorillonite engenders an opposite trend. The whole nanocomposites whose gelation temperature can be tuned by both the nature and concentration of the nanosheets were successfully photopolymerized allowing the formation of a 3D structure containing a large content of water. The results obtained in this study open new perspectives for possible uses of hydrogel-based nanocomposites as embedding matrixes for bio-organisms.

本文言語English
ページ(範囲)753-761
ページ数9
ジャーナルRSC Advances
12
2
DOI
出版ステータスPublished - 2021 12月 24

ASJC Scopus subject areas

  • 化学 (全般)
  • 化学工学(全般)

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