Preparation of wettability modulated thermoresponsive surfaces by ATRP and elution control of biomolecules

Naokazu Idota*, Akihiko Kikuchi, Jun Kobayashi, Kiyotaka Sakai, Teruo Okano

*この研究の対応する著者

研究成果: Conference contribution

抄録

Temperature-dependent aqueous wettability of poly(N-isopropylacrylamide) (PIPAAm)-grafted surfaces was regulated by thickness of graft polymer layer and architecture of polymer chains utilizing surface-initiated atom transfer radical polymerization (ATRP). Hydrophilic property on the PIPAAm-grafted surfaces depends on polymer layer thickness at low temperature range. More hydrophobic surface properties were observed for poly (n-butyl methacrylate) (PBMA)-b-PIPAAm-grafted surfaces above PIPAAm's transition temperature. Applying surface-initiated ATRP of IPAAm to inner surfaces of microcapillaries, the retention times of steroids were controlled solely by temperature changes. Testosterone showed stronger interaction with more hydrophobic PBMA-e-PIPAAm-grafted surfaces above PIPAAm's LCST, and baseline separation of steroids was successfully achieved within 10min by only temperature alterations.

本文言語English
ホスト出版物のタイトルPolymer Preprints, Japan
ページ5147-5148
ページ数2
54
2
出版ステータスPublished - 2005
イベント54th SPSJ Symposium on Macromolecules - Yamagata
継続期間: 2005 9 202005 9 22

Other

Other54th SPSJ Symposium on Macromolecules
CityYamagata
Period05/9/2005/9/22

ASJC Scopus subject areas

  • 工学(全般)

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