Printing support hydrogels for creating vascular-like structures in stacked cell sheets

Ryu ichiro Tanaka, Katsuhisa Sakaguchi, Shinjiro Umezu*

*この研究の対応する著者

研究成果: Article査読

2 被引用数 (Scopus)

抄録

Vascular structures are essential for the survival of thick artificial three-dimensional (3D) tissues. However, it is difficult to create high-cell-density artificial tissue with vascular structures of a few hundred micrometers in diameter. Bioprinting technology can create artificial 3D tissues with vascular structures of a few hundred micrometers in diameter, but the cell density of bio-printed artificial 3D tissues is low. On the other hand, cell sheet technology can create high-cell-density artificial 3D tissues by stacking, but it is not possible to set small vascular structures at any place. In this study, we successfully demonstrated high-cell-density artificial 3D tissues with vascular-like structures by stacking cell sheets combined with bioprinting technology.

本文言語English
ページ(範囲)199-203
ページ数5
ジャーナルArtificial Life and Robotics
25
2
DOI
出版ステータスPublished - 2020 5月 1

ASJC Scopus subject areas

  • 生化学、遺伝学、分子生物学(全般)
  • 人工知能

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