Prolongation effects of hemostatic ability of poly(ethyleneglycol)-modified polymerized albumin particles carrying fibrinogen-γ chain dodecapeptide (H12) as platelet substitutes

Toshinori Fujie, Yousuke Okamura, Shinji Takeoka, Makoto Handa, Yasuo Ikeda

研究成果: Paper

抜粋

We conjugated dodecapeptide (H12), which was a part of the amino acid sequence of fibrinogen, to the terminal of polyethyleneglycol (PEG) chains of the PEG-modified polymerized albumin particles(polyAlb), and confirmed that they showed a significant hemostatic effect even 3hrs after injection(40mg/kg) in thrombocytopenic rats.

元の言語English
ページ数1
出版物ステータスPublished - 2006 10 19
イベント55th SPSJ Annual Meeting - Nagoya, Japan
継続期間: 2006 5 242006 5 26

Conference

Conference55th SPSJ Annual Meeting
Japan
Nagoya
期間06/5/2406/5/26

ASJC Scopus subject areas

  • Engineering(all)

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