Protein-protein interactions in solution and their interplay with protein specific functions

Takaaki Sato*, Toshiko Fukasawa, Togo Shimozawa, Teruyuki Komatsu, Hiromi Sakai, Shin'Ichi Ishiwata

*この研究の対応する著者

研究成果: Article査読

2 被引用数 (Scopus)

抄録

We summarize recent developments of our small angle scattering studies on protein-protein interactions in solution. We have been focusing especially on representative proteins that function at exceptionally high concentration in human body, whose collective nature, rather than a specialized function of an isolated single molecule, plays an important role for their specific biological functions; for instance, human serum albumin (HSA), actin, and human hemoglobin (Hb). We use a static structure factor analysis, which offers information about spatial distributions of the proteins, as well as a Fourier inversion technique for the form factor, giving a real-space picture of the protein assemblies.

本文言語English
論文番号SA002
ジャーナルJournal of the Physical Society of Japan
81
SUPPL. A
出版ステータスPublished - 2012 9月
外部発表はい

ASJC Scopus subject areas

  • 物理学および天文学(全般)

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