Pyrizomicin A and B: Structure and bioactivity of new thiazolyl pyridines from Lechevalieria aerocolonigenes K10-0216

Toru Kimura, Yuki Inahashi, Hirotaka Matsuo, Takuya Suga, Masato Iwatsuki, Kazuro Shiomi, Yoko Takahashi, Satoshi Omura, Takuji Nakashima*

*この研究の対応する著者

研究成果: Article査読

8 被引用数 (Scopus)

抄録

Two new antibiotics, designated pyrizomicin A and B, were isolated from the cultured broth of a rare actinomycete strain, Lechevalieria aerocolonigenes K10-0216, by silica gel and HPLC purification. The chemical structures of pyrizomicin A and B were elucidated as new thiazolyl pyridine compounds by nuclear magnetic resonance and mass spectrometry. Pyrizomicin A and B both showed antimicrobial activity.

本文言語English
ページ(範囲)606-608
ページ数3
ジャーナルJournal of Antibiotics
71
6
DOI
出版ステータスPublished - 2018 6月 1
外部発表はい

ASJC Scopus subject areas

  • 薬理学
  • 創薬

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