Quasi-in vivo heart electrocardiogram measurement of ST period using convolution of cell network extracellular field potential propagation in lined-up cardiomyocyte cell-network circuit

Tomoyuki Kaneko, Fumimasa Nomura, Kenji Yasuda

研究成果: Article

6 引用 (Scopus)

抄録

A model for the quasi-in vivo heart electrocardiogram (ECG) measurement of the ST period has been developed. As the part of ECG data at the ST period is the convolution of the extracellular field potentials (FPs) of cardiomyocytes in a ventricle, we have fabricated a lined-up cardiomyocyte cell-network on a lined-up microelectrode array and a circular microelectrode in an agarose microchamber, and measured the convoluted FPs). When the ventricular tachyarrhythmias of beating occurred in the cardiomyocyte network, the convoluted FP profile showed similar arrhythmia ECG-like profiles, indicating the convoluted FPs) of the in vitro cell network include both the depolarization data and the propagation manner of beating in the heart.

元の言語English
記事番号070213
ジャーナルJapanese Journal of Applied Physics
50
発行部数7 PART 1
DOI
出版物ステータスPublished - 2011 7
外部発表Yes

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electrocardiography
potential fields
Electrocardiography
Convolution
convolution integrals
Microelectrodes
propagation
Networks (circuits)
cells
Bioelectric potentials
Depolarization
arrhythmia
profiles
depolarization

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

これを引用

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