Rate parameters for oxygen and carbon monoxide binding to a liposome-embedded heme were measured under physiological conditions (pH 7.0 at 37 °C) by stopped-flow spectrophotometry. The rate constants were similar to those of red blood cells in suspension. It is concluded that liposome-embedded heme is a suitable model to study the binding of gaseous molecules to red blood cells.
|ジャーナル||Journal of the Chemical Society, Dalton Transactions|
|出版物ステータス||Published - 1985|
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