Regioselective synthesis of piceatannol from resveratrol: Catalysis by two-component flavin-dependent monooxygenase HpaBC in whole cells

Toshiki Furuya; Kuniki Kino

doi:10.1016/j.tetlet.2014.03.076

Regioselective synthesis of piceatannol from resveratrol: Catalysis by two-component flavin-dependent monooxygenase HpaBC in whole cells

Toshiki Furuya^*, Kuniki Kino

^*この研究の対応する著者

先進理工学部

研究成果: Article › 査読

26 被引用数 (Scopus)

抄録

Piceatannol, a valuable biologically active stilbene derivative, was efficiently synthesized from resveratrol. Whole-cell catalysis with HpaBC monooxygenase enabled the regioselective hydroxylation of resveratrol to produce 23 mM (5.2 g L^-1) of piceatannol.

本文言語	English
ページ（範囲）	2853-2855
ページ数	3
ジャーナル	Tetrahedron Letters
巻	55
号	17
DOI	https://doi.org/10.1016/j.tetlet.2014.03.076
出版ステータス	Published - 2014 4月 23

ASJC Scopus subject areas

生化学
創薬
有機化学

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10.1016/j.tetlet.2014.03.076

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引用スタイル

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abstract = "Piceatannol, a valuable biologically active stilbene derivative, was efficiently synthesized from resveratrol. Whole-cell catalysis with HpaBC monooxygenase enabled the regioselective hydroxylation of resveratrol to produce 23 mM (5.2 g L-1) of piceatannol.",

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KW - Monooxygenase

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