Regulation of chromatin structure by curved DNA: How activator binding sites become accessible

研究成果: Chapter

抜粋

A single somatic cell of humans contains DNA fibers of a total length of approximately 2 m, which are compacted, without entanglement, into the nucleus of approximately 1×10-5 m in diameter. To greater or lesser degrees, all organisms compact their DNA. Biologically important DNA regions, such as the origins of DNA replication, regulatory regions of transcription, and recombination loci, must all be compacted. The tightly constrained DNA, however, presents the appropriate environment for replication, transcription, and recombination to take place.

元の言語English
ホスト出版物のタイトルNuclear Dynamics
ホスト出版物のサブタイトルMolecular Biology and Visualization of the Nucleus
出版者Springer Japan
ページ227-238
ページ数12
ISBN(電子版)9784431301301
ISBN(印刷物)4431300546, 9784431300540
DOI
出版物ステータスPublished - 2007 1 1

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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  • これを引用

    Ohyama, T. (2007). Regulation of chromatin structure by curved DNA: How activator binding sites become accessible. : Nuclear Dynamics: Molecular Biology and Visualization of the Nucleus (pp. 227-238). Springer Japan. https://doi.org/10.1007/978-4-431-30130-1_10