Relationship between blood adipocytokines and resting energy expenditure in young and elderly women

Chiyoko Usui, Eri Takahashi, Yuko Gando, Kiyoshi Sanada, Jun Oka, Motohiko Miyachi, Izumi Tabata, Mitsuru Higuchi*


研究成果: Article査読

7 被引用数 (Scopus)


It has been demonstrated in a previous study that resting energy expenditure (REE) is associated with adiponectin levels in the blood. However, body composition was not taken into consideration in that study. The purpose of the present study was to again investigate the relationship between blood adipocytokines and REE, adjusted by body composition, in both young and elderly women. REE and blood adipocytokines were measured in 115 young (age: 22.3±2.1 y, BMI: 21.3±1.9 kg/m2) and 71 elderly (63.4±6.5 y, 22.9±2.3 kg/m2) women. Dual energy X-ray absorptiometry was used to measure percent body fat. Fat mass and fat free mass (FFM) were calculated. REE (kcal/d and kcal/kg BW/d) was lower in elderly women than in young women, but no significant difference was observed in REE, expressed as kcal/kg FFM/d, between the two groups. Although elderly women had a higher percent body fat and higher serum leptin concentrations than young women, plasma adiponectin concentrations did not differ between young and elderly women. In elderly women, REE (kcal/d) was significantly and inversely correlated with plasma adiponectin concentration (r=-0.386, p<0.001), but REE expressed per kilogram of BW or FFM was not significantly correlated. Furthermore, no significant correlation was observed between REE (kcal/d) and concentrations of plasma adiponectin or serum leptin, after adjusting for potential confounders such as body composition and hormones, in either age group. These results suggest that adipocytokines do not influence REE in adult women.

ジャーナルJournal of Nutritional Science and Vitaminology
出版ステータスPublished - 2007 12月

ASJC Scopus subject areas

  • 医学(その他)
  • 栄養および糖尿病


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