TY - JOUR
T1 - Relationship between blood adipocytokines and resting energy expenditure in young and elderly women
AU - Usui, Chiyoko
AU - Takahashi, Eri
AU - Gando, Yuko
AU - Sanada, Kiyoshi
AU - Oka, Jun
AU - Miyachi, Motohiko
AU - Tabata, Izumi
AU - Higuchi, Mitsuru
PY - 2007/12
Y1 - 2007/12
N2 - It has been demonstrated in a previous study that resting energy expenditure (REE) is associated with adiponectin levels in the blood. However, body composition was not taken into consideration in that study. The purpose of the present study was to again investigate the relationship between blood adipocytokines and REE, adjusted by body composition, in both young and elderly women. REE and blood adipocytokines were measured in 115 young (age: 22.3±2.1 y, BMI: 21.3±1.9 kg/m2) and 71 elderly (63.4±6.5 y, 22.9±2.3 kg/m2) women. Dual energy X-ray absorptiometry was used to measure percent body fat. Fat mass and fat free mass (FFM) were calculated. REE (kcal/d and kcal/kg BW/d) was lower in elderly women than in young women, but no significant difference was observed in REE, expressed as kcal/kg FFM/d, between the two groups. Although elderly women had a higher percent body fat and higher serum leptin concentrations than young women, plasma adiponectin concentrations did not differ between young and elderly women. In elderly women, REE (kcal/d) was significantly and inversely correlated with plasma adiponectin concentration (r=-0.386, p<0.001), but REE expressed per kilogram of BW or FFM was not significantly correlated. Furthermore, no significant correlation was observed between REE (kcal/d) and concentrations of plasma adiponectin or serum leptin, after adjusting for potential confounders such as body composition and hormones, in either age group. These results suggest that adipocytokines do not influence REE in adult women.
AB - It has been demonstrated in a previous study that resting energy expenditure (REE) is associated with adiponectin levels in the blood. However, body composition was not taken into consideration in that study. The purpose of the present study was to again investigate the relationship between blood adipocytokines and REE, adjusted by body composition, in both young and elderly women. REE and blood adipocytokines were measured in 115 young (age: 22.3±2.1 y, BMI: 21.3±1.9 kg/m2) and 71 elderly (63.4±6.5 y, 22.9±2.3 kg/m2) women. Dual energy X-ray absorptiometry was used to measure percent body fat. Fat mass and fat free mass (FFM) were calculated. REE (kcal/d and kcal/kg BW/d) was lower in elderly women than in young women, but no significant difference was observed in REE, expressed as kcal/kg FFM/d, between the two groups. Although elderly women had a higher percent body fat and higher serum leptin concentrations than young women, plasma adiponectin concentrations did not differ between young and elderly women. In elderly women, REE (kcal/d) was significantly and inversely correlated with plasma adiponectin concentration (r=-0.386, p<0.001), but REE expressed per kilogram of BW or FFM was not significantly correlated. Furthermore, no significant correlation was observed between REE (kcal/d) and concentrations of plasma adiponectin or serum leptin, after adjusting for potential confounders such as body composition and hormones, in either age group. These results suggest that adipocytokines do not influence REE in adult women.
KW - Adiponectin
KW - Age
KW - Female adults
KW - Leptin
KW - Resting energy expenditure
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U2 - 10.3177/jnsv.53.529
DO - 10.3177/jnsv.53.529
M3 - Article
C2 - 18202542
AN - SCOPUS:38549104929
VL - 53
SP - 529
EP - 535
JO - The Journal of vitaminology
JF - The Journal of vitaminology
SN - 0301-4800
IS - 6
ER -