@article{c33863e15c964fcb93ae1d406e9169e6,
title = "Relationship between macrophage differentiation and the chemotactic activity toward damaged myoblast cells",
abstract = "We investigated the effect of macrophage differentiation on the chemotactic activity to invade local damaged myoblasts using in vitro models of muscle injury. We found that: 1) the chemotactic activity of macrophages toward areas of damaged myoblasts might be induced more by live myoblasts than dead ones, 2) the chemotactic activity of macrophages is not due to velocity, but depends on the directionality toward damaged myoblast cells, and 3) macrophage differentiation strongly influence the chemotactic activity toward damaged myoblast cells through the expression of CCR2 and/or F-actin.",
keywords = "CCR2, Dexamethasone, F-actin, Lipopolysaccharide, TAXIScan",
author = "Masataka Uchida and Eri Oyanagi and Motohiko Miyachi and Akira Yamauchi and Hiromi Yano",
note = "Funding Information: This work was supported by Grants-in-Aid for Scientific Research from the Ministry of Education, Science, Sports and Culture of Japan ( A-23240089 and C-24500878 ) and the Interdepartmental Research Fund of Kawasaki University of Medical Welfare (to H.Y.). We thank the staff of the Environment Research Medical Center, the Tissue & Electromagnetic Microscopy Center, and the Tissue Culture and Immunity Center of Kawasaki Medical School.",
year = "2013",
doi = "10.1016/j.jim.2013.04.007",
language = "English",
volume = "393",
pages = "61--69",
journal = "Journal of Immunological Methods",
issn = "0022-1759",
publisher = "Elsevier",
number = "1-2",
}