Relationships between lifestyle factors and neutrophil functions in the elderly

Kazumasa Tsukamoto*, Katsuhiko Suzuki, Kazuhiko Machida, Chinatsu Saiki, Rumiko Murayama, Minoru Sugita

*この研究の対応する著者

研究成果査読

13 被引用数 (Scopus)

抄録

We investigated the relationships between neutrophil functions and lifestyle factors in the elderly. The subjects (84 males, 73.9±5.8 years old; and 63 females, 70.0±4.6 years old) belonged to a recreational seniors club in Japan. Investigations of the subjects' stress, exercise habits, smoking habits, and alcohol-drinking habits were performed. The phagocytosis and superoxide productivity of the neutrophils were measured with a nitroblue tetrazolium (NBT) reduction test. In addition, leukocyte counts and serum total protein (TP) levels were determined. The results revealed that aging, high serum levels, and stress-coping factors (e.g., having hobbies, keeping pets, and close links with friends or family) significantly correlated with preferable neutrophil functions. In addition, significant effects of lifestyle factors on the balance between phagocytosis and subsequent superoxide production were observed. Thus, the results of the present study suggest that there are correlations between neutrophil functions and lifestyle factors in the elderly.

本文言語English
ページ(範囲)266-272
ページ数7
ジャーナルJournal of Clinical Laboratory Analysis
16
5
DOI
出版ステータスPublished - 2002
外部発表はい

ASJC Scopus subject areas

  • 免疫アレルギー学
  • 血液学
  • 公衆衛生学、環境および労働衛生
  • 臨床生化学
  • 医療検査技術
  • 生化学、医学
  • 微生物学(医療)

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