Reoxygenation in tumor tissues after X-ray or carbon-12 irradiation

Takeshi Fukawa*, Koji Takematsu, Kotaro Oka, Nobuyuki Miyahara, Sachiko Koike, Koichi Ando, Hirosuke Kobayashi, Kazuo Tanishita

*この研究の対応する著者

研究成果: Chapter

抄録

We measured directly the partial pressure of oxygen (pO 2) in new fibrosarcoma (NFSa) tumors grown in C3H/He mice using microcoaxial O 2 electrodes in vivo. The pO 2 in tumors was monitored after a single dose of X-ray or carbon-12 irradiation. After irradiation, tumor volume temporally shrinked, and pO 2 simultaneously increased. Carbon-12 irradiation reoxygenated tumors between the 1st and 9th day after the irradiation, while x-ray irradiation reoxygenated tumors between the 3rd and 8th day. We found that reoxygenation period after carbon-12 irradiation started earlier and continued longer than X-ray irradiation.

本文言語English
ホスト出版物のタイトルAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
ページ371-372
ページ数2
39
出版ステータスPublished - 1998
外部発表はい

ASJC Scopus subject areas

  • 工学(全般)

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