TY - JOUR
T1 - Repulsive effects of hydrophobic diamond thin films on biomolecule detection
AU - Ruslinda, A. Rahim
AU - Ishiyama, Y.
AU - Penmatsa, V.
AU - Ibori, S.
AU - Kawarada, H.
N1 - Funding Information:
This work was supported by a Grant-in-Aid from GCOE Research from the Ministry of Education, Culture, Sports, Science, and Technology , Japan, a Grant-in-Aid for Fundamental Research A ( 23246069 ) from Japan Society for the Promotion of Science , a Grant-in Aid for Research Acceleration Collaboration Exchange 9017-00022 from Ministry of Education Malaysia, and L’Oreal Women in Science Fellowship 2013 .
Publisher Copyright:
© 2014 Elsevier B.V. All rights reserved.
PY - 2015/2/15
Y1 - 2015/2/15
N2 - The repulsive effect of hydrophobic diamond thin film on biomolecule detection, such as single-nucleotide polymorphisms and human immunodeficiency virus type 1 trans-activator of transcription peptide protein detection, was investigated using a mixture of a fluorine-, amine-, and hydrogen-terminated diamond surfaces. These chemical modifications lead to the formation of a surface that effectively resists the nonspecific adsorption of proteins and other biomolecules. The effect of fluorine plasma treatment on elemental composition was also investigated via X-ray photoelectron spectroscopy (XPS). XPS results revealed a fluorocarbon layer on the diamond thin films. The contact angle measurement results indicated that the fluorine-treated diamond thin films were highly hydrophobic with a surface energy value of ∼25 mN/m.
AB - The repulsive effect of hydrophobic diamond thin film on biomolecule detection, such as single-nucleotide polymorphisms and human immunodeficiency virus type 1 trans-activator of transcription peptide protein detection, was investigated using a mixture of a fluorine-, amine-, and hydrogen-terminated diamond surfaces. These chemical modifications lead to the formation of a surface that effectively resists the nonspecific adsorption of proteins and other biomolecules. The effect of fluorine plasma treatment on elemental composition was also investigated via X-ray photoelectron spectroscopy (XPS). XPS results revealed a fluorocarbon layer on the diamond thin films. The contact angle measurement results indicated that the fluorine-treated diamond thin films were highly hydrophobic with a surface energy value of ∼25 mN/m.
KW - Biomolecules
KW - Chemical modification
KW - Diamond film
KW - Fluorine
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U2 - 10.1016/j.apsusc.2014.12.011
DO - 10.1016/j.apsusc.2014.12.011
M3 - Article
AN - SCOPUS:84922233840
SN - 0169-4332
VL - 328
SP - 314
EP - 318
JO - Applied Surface Science
JF - Applied Surface Science
ER -
