@article{9c215981b52f4b97b6aa074624fb7889,
title = "Research on Au(I)-catalyzed ene-yne cycloisomerization for construction of quassinoid scaffold",
abstract = "Compounds that undergo Au(I)-catalyzed cycloisomerizations affording tetracyclic products that can be converted into compounds with the skeleton of bruceantin are described. The Au(I)-catalyzed cycloisomerizations reported herein are hindered by a 1,3-diaxial interaction between the substituent and the methyl group in the transition state. The use of small substituents was found to increase the yield of the desired product, while the reaction of substrates with large substituents afford undesired constitutional isomers.",
keywords = "Au(I)-catalysis, Bruceantin, Ene-yne cycloisomerization, Quassinoid, Stereoselective",
author = "Yuta Oki and Masahisa Nakada",
note = "Funding Information: We acknowledge supports of the Materials Characterization Central Laboratory, Waseda University – Japan, for characterization of new compounds. This work was financially supported in part by the Grant-in-Aid for Scientific Research on Innovative Areas 2707 Middle molecular strategy from MEXT – Japan and a Waseda University Grant for Special Research Projects. A Publisher Copyright: {\textcopyright} 2018 Elsevier Ltd",
year = "2018",
month = mar,
day = "7",
doi = "10.1016/j.tetlet.2018.01.069",
language = "English",
volume = "59",
pages = "926--929",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "10",
}