抄録
Hyperprocessing is defined as a further processing of mature RNA that produces another functional RNA. Hyperprocessing occurs in Drosophila cells. In the transposon copia-related retrovirus-like particles of Drosophila, a 39-nucleotide-long fragment from the 5′-region of Drosophila initiator methionine tRNA is used as the primer for copia minus-strand reverse transcription. This primer tRNA fragment is thought to be produced by cleavage within the mature tRNA sequence. We found that the catalytic RNA subunit of RNase P catalyzes this hyperprocessing in vitro and that this cleavage is dependent of the occurrence of an altered conformation of the tRNA substrate. In this review, I will summarize our work from the finding of the functional RNA fragment to the finding of a dynamic tRNA structure
本文言語 | English |
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ページ(範囲) | 171-175 |
ページ数 | 5 |
ジャーナル | Molecular Biology Reports: An International Journal on Molecular and Cellular Biology |
巻 | 22 |
号 | 2 |
DOI | |
出版ステータス | Published - 1995 |
外部発表 | はい |
ASJC Scopus subject areas
- 遺伝学
- 分子生物学