抄録
F1-ATPase, a water-soluble portion of ATP synthase, is a fully reversible rotary molecular machine in which a central γ subunit rotates inside a cylinder made of three α and three β subunits alternately arranged. This motor rotates counterclockwise by hydrolyzing ATP in three catalytic sites but synthesizes ATP when forced to rotate clockwise by an external force. Single-molecule studies have revealed how the chemical reactions that occur in the three catalytic sites are coupled to mechanical rotation.
本文言語 | English |
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ホスト出版物のタイトル | Comprehensive Biophysics |
出版社 | Elsevier Inc. |
ページ | 35-49 |
ページ数 | 15 |
巻 | 8 |
ISBN(印刷版) | 9780080957180 |
DOI | |
出版ステータス | Published - 2012 |
外部発表 | はい |
ASJC Scopus subject areas
- 生化学、遺伝学、分子生物学(全般)