Rotational dynamics of immunoglobulins with fluorescent haptens on a membrane surface

Hiroshi Osada; Mamoru Nakanishi; Masamichi Tsuboi; Kazuhiko Kinosita; Akira Ikegami

doi:10.1016/0005-2736(84)90097-X

Rotational dynamics of immunoglobulins with fluorescent haptens on a membrane surface

Hiroshi Osada, Mamoru Nakanishi^*, Masamichi Tsuboi, Kazuhiko Kinosita, Akira Ikegami

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研究成果: Article › 査読

6 被引用数 (Scopus)

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The rotational dynamics of rabbit immunoglobulin G with fluorescent lipid haptens on a membrane surface has been studied by nanosecond fluorescence emission anisotropic spectroscopy. It has been found that the rotational angles of the antibody are very restricted on the membrane, but that the rotation rate itself is not appreciably lower than that in solution, and is independent of the membrane fluidity.

本文言語	English
ページ（範囲）	321-324
ページ数	4
ジャーナル	BBA - Biomembranes
巻	773
号	2
DOI	https://doi.org/10.1016/0005-2736(84)90097-X
出版ステータス	Published - 1984 6月 27
外部発表	はい

ASJC Scopus subject areas

生化学
生物理学
細胞生物学
医学（全般）

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10.1016/0005-2736(84)90097-X

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abstract = "The rotational dynamics of rabbit immunoglobulin G with fluorescent lipid haptens on a membrane surface has been studied by nanosecond fluorescence emission anisotropic spectroscopy. It has been found that the rotational angles of the antibody are very restricted on the membrane, but that the rotation rate itself is not appreciably lower than that in solution, and is independent of the membrane fluidity.",

keywords = "(Liposome), Fluorescence anisotropy, Immunoglobulin, Lipid hapten, Membrane fluidity, Rotational dynamics",

author = "Hiroshi Osada and Mamoru Nakanishi and Masamichi Tsuboi and Kazuhiko Kinosita and Akira Ikegami",

year = "1984",

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T1 - Rotational dynamics of immunoglobulins with fluorescent haptens on a membrane surface

AU - Osada, Hiroshi

AU - Nakanishi, Mamoru

AU - Tsuboi, Masamichi

AU - Kinosita, Kazuhiko

AU - Ikegami, Akira

PY - 1984/6/27

Y1 - 1984/6/27

N2 - The rotational dynamics of rabbit immunoglobulin G with fluorescent lipid haptens on a membrane surface has been studied by nanosecond fluorescence emission anisotropic spectroscopy. It has been found that the rotational angles of the antibody are very restricted on the membrane, but that the rotation rate itself is not appreciably lower than that in solution, and is independent of the membrane fluidity.

AB - The rotational dynamics of rabbit immunoglobulin G with fluorescent lipid haptens on a membrane surface has been studied by nanosecond fluorescence emission anisotropic spectroscopy. It has been found that the rotational angles of the antibody are very restricted on the membrane, but that the rotation rate itself is not appreciably lower than that in solution, and is independent of the membrane fluidity.

KW - (Liposome)

KW - Fluorescence anisotropy

KW - Immunoglobulin

KW - Lipid hapten

KW - Membrane fluidity

KW - Rotational dynamics

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JO - Biochimica et Biophysica Acta - Biomembranes

JF - Biochimica et Biophysica Acta - Biomembranes

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Rotational dynamics of immunoglobulins with fluorescent haptens on a membrane surface

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