Salivary 3-methoxy-4-hydroxyphenylglycol increases after awakening in healthy young adults

Nagisa Sugaya*, Shuhei Izawa, Ryuichiro Yamamoto, Namiko Ogawa, Jumpei Yajima, Hisayoshi Okamura, Satoshi Horiuchi, Akira Tsuda, Shinobu Nomura

*この研究の対応する著者

    研究成果: Article査読

    4 被引用数 (Scopus)

    抄録

    Levels of 3-methoxy-4-hydroxyphenylglycol (MHPG) may reflect central noradrenergic activity. In this study, we investigated salivary MHPG changes after awakening, and explored their relationships with cortisol and peripheral autonomic activity. The participants were 25 college students. Saliva samples were collected on awakening and 30min after awakening to determine MHPG and cortisol. Ambulatory electrocardiograms were obtained to assess heart rate, cardiac sympathetic index (CSI), and cardiac vagal index (CVI) before and after awakening. MHPG levels increased significantly during the first 30min after awakening. Similarly, cortisol, heart rate, and CSI increased during the 30min after awakening, but changes in MHPG did not correlate with changes in cortisol, heart rate, CSI, and CVI during that period. This study demonstrated that salivary MHPG levels increase after awakening, in common with cortisol, heart rate, and cardiac sympathetic activity.

    本文言語English
    ページ(範囲)425-428
    ページ数4
    ジャーナルPsychophysiology
    52
    3
    DOI
    出版ステータスPublished - 2015 3 1

    ASJC Scopus subject areas

    • 生理学
    • 生理学(医学)
    • 実験心理学および認知心理学
    • 神経心理学および生理心理学
    • 人文科学(その他)
    • 発達心理学および教育心理学

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