TY - JOUR
T1 - Salivary cortisol and DHEA reactivity to psychosocial stress in socially anxious males
AU - Shirotsuki, Kentaro
AU - Izawa, Shuhei
AU - Sugaya, Nagisa
AU - Yamada, Kosuke Chris
AU - Ogawa, Namiko
AU - Ouchi, Yuko
AU - Nagano, Yuichiro
AU - Nomura, Shinobu
PY - 2009/5
Y1 - 2009/5
N2 - The purpose of the present study was to examine Hypothalamus-Pituitary-Adrenal (HPA) axis reactivity in social anxiety. The present study used a standardized psychosocial stress protocol (the Trier Social Stress Test; TSST; [Kirschbaum, C., Pirke, K.M., Hellhammer, D.H., 1993. The 'Trier Social Stress Test'-a tool for investigating psychobiological stress responses in a laboratory setting. Neuropsychobiology 28, 76-81.]) with 11 higher-social-anxiety and 11 lower-social-anxiety male college students. Psychological responses and salivary cortisol and dehydroepiandrosterone (DHEA) reactivity and cortisol/DHEA ratio were assessed at seven different times. The results showed that there was a significantly lower cortisol responsiveness in the higher social anxiety group but there was no significant difference of DHEA responsiveness. Further analyses showed lower responses for the cortisol/DHEA ratio in the higher-social-anxiety group to the TSST. These results suggest that there may be reduced HPA axis reactivity to psychosocial stress in socially anxious people.
AB - The purpose of the present study was to examine Hypothalamus-Pituitary-Adrenal (HPA) axis reactivity in social anxiety. The present study used a standardized psychosocial stress protocol (the Trier Social Stress Test; TSST; [Kirschbaum, C., Pirke, K.M., Hellhammer, D.H., 1993. The 'Trier Social Stress Test'-a tool for investigating psychobiological stress responses in a laboratory setting. Neuropsychobiology 28, 76-81.]) with 11 higher-social-anxiety and 11 lower-social-anxiety male college students. Psychological responses and salivary cortisol and dehydroepiandrosterone (DHEA) reactivity and cortisol/DHEA ratio were assessed at seven different times. The results showed that there was a significantly lower cortisol responsiveness in the higher social anxiety group but there was no significant difference of DHEA responsiveness. Further analyses showed lower responses for the cortisol/DHEA ratio in the higher-social-anxiety group to the TSST. These results suggest that there may be reduced HPA axis reactivity to psychosocial stress in socially anxious people.
KW - Cortisol
KW - Dehydroepiandrosterone
KW - HPA axis
KW - Social anxiety disorder
KW - Trier Social Stress Test
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U2 - 10.1016/j.ijpsycho.2008.12.010
DO - 10.1016/j.ijpsycho.2008.12.010
M3 - Article
C2 - 19141305
AN - SCOPUS:64849105438
VL - 72
SP - 198
EP - 203
JO - International Journal of Psychophysiology
JF - International Journal of Psychophysiology
SN - 0167-8760
IS - 2
ER -