Seasonal changes in the synthesis of the neurosteroid 7α- hydroxypregnenolone stimulating locomotor activity in newts

Shogo Haraguchi, Masahiro Matsunaga, Teppei Koyama, Jean Luc Do Rego, Kazuyoshi Tsutsui

    研究成果: Conference contribution

    10 引用 (Scopus)

    抜粋

    We recently found that the newt brain actively produces 7α-hydroxypregnenolone, a novel amphibian neurosteroid stimulating locomotor activity. It is well known that locomotor activity of male newts increases during the breeding period. To understand the physiological role of 7α-hydroxypregnenolone, we investigated seasonal changes in 7α-hydroxypregnenolone synthesis in the brain of male newts. Interestingly, 7α-hydroxypregnenolone synthesis in the brain showed marked changes during the annual breeding cycle, with a maximal level in the breeding period when locomotor activity of male newts increases. These results suggest that 7α-hydroxypregnenolone induces seasonal locomotor changes in male newts.

    元の言語English
    ホスト出版物のタイトルAnnals of the New York Academy of Sciences
    ページ410-413
    ページ数4
    1163
    DOI
    出版物ステータスPublished - 2009 4

    出版物シリーズ

    名前Annals of the New York Academy of Sciences
    1163
    ISSN(印刷物)00778923
    ISSN(電子版)17496632

    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)

    フィンガープリント Seasonal changes in the synthesis of the neurosteroid 7α- hydroxypregnenolone stimulating locomotor activity in newts' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用

    Haraguchi, S., Matsunaga, M., Koyama, T., Rego, J. L. D., & Tsutsui, K. (2009). Seasonal changes in the synthesis of the neurosteroid 7α- hydroxypregnenolone stimulating locomotor activity in newts. : Annals of the New York Academy of Sciences (巻 1163, pp. 410-413). (Annals of the New York Academy of Sciences; 巻数 1163). https://doi.org/10.1111/j.1749-6632.2008.03621.x