Selective detection and transport of fully matched DNA by DNA-loaded microtubule and kinesin motor protein

Shu Taira; Yong Zhong Du; Yuichi Hiratsuka; Kaoru Konishi; Tai Kubo; Taro Q.P. Uyeda; Noboru Yumoto; Masato Kodaka

doi:10.1002/bit.21055

Selective detection and transport of fully matched DNA by DNA-loaded microtubule and kinesin motor protein

Shu Taira, Yong Zhong Du, Yuichi Hiratsuka, Kaoru Konishi, Tai Kubo, Taro Q.P. Uyeda, Noboru Yumoto, Masato Kodaka^*

^*この研究の対応する著者

研究成果: Article › 査読

50 被引用数 (Scopus)

抄録

DNA-loaded microtubules (MTs) moving on a kinesin motor protein-coated substrate can selectively hybridize with a target fully matched DNA over single-base mismatched DNA and transport it. This technique is capable of collecting target biomolecules toward one point site to design new methodology of DNA analysis.

本文言語	English
ページ（範囲）	533-538
ページ数	6
ジャーナル	Biotechnology and bioengineering
巻	95
号	3
DOI	https://doi.org/10.1002/bit.21055
出版ステータス	Published - 2006 10月 20
外部発表	はい

ASJC Scopus subject areas

バイオテクノロジー
バイオエンジニアリング
応用微生物学とバイオテクノロジー

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10.1002/bit.21055

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AU - Taira, Shu

AU - Du, Yong Zhong

AU - Hiratsuka, Yuichi

AU - Konishi, Kaoru

AU - Kubo, Tai

AU - Uyeda, Taro Q.P.

AU - Yumoto, Noboru

AU - Kodaka, Masato

PY - 2006/10/20

Y1 - 2006/10/20

N2 - DNA-loaded microtubules (MTs) moving on a kinesin motor protein-coated substrate can selectively hybridize with a target fully matched DNA over single-base mismatched DNA and transport it. This technique is capable of collecting target biomolecules toward one point site to design new methodology of DNA analysis.

AB - DNA-loaded microtubules (MTs) moving on a kinesin motor protein-coated substrate can selectively hybridize with a target fully matched DNA over single-base mismatched DNA and transport it. This technique is capable of collecting target biomolecules toward one point site to design new methodology of DNA analysis.

KW - DNA-loaded microtubules

KW - Motor protein

KW - SNP

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Selective detection and transport of fully matched DNA by DNA-loaded microtubule and kinesin motor protein

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