抄録
We determined the complete nucleotide sequence (6125 bp) of a full-length member of human KpnI family, designated TβG41, which is located about 3 kb downstream from the β-globin gene. Comparison of the sequence with the KpnI family sequence compiled by Singer revealed that a new 131 bp sequence is present in the TβG41. Hybridization analyses showed that a few thousand of human KpnI family members are carrying this additional sequence. Computer search of DNA databases for TβG41-homologous sequence showed that some TβG41-homologous sequences were closely associated with pseudogenes. The TβG41 sequence also showed significant sequence homology with ChBlyml, a transferrin-like transforming gene of chicken. Furthermore, an amino acid sequence deduced from the TβG41 nucleotide sequence revealed a relatively-high homology to those of human transferrin and lactotransferrin.
本文言語 | English |
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ページ(範囲) | 7813-7827 |
ページ数 | 15 |
ジャーナル | Nucleic Acids Research |
巻 | 13 |
号 | 21 |
DOI | |
出版ステータス | Published - 1985 11 11 |
外部発表 | はい |
ASJC Scopus subject areas
- Statistics, Probability and Uncertainty
- Applied Mathematics
- Health, Toxicology and Mutagenesis
- Toxicology
- Genetics(clinical)
- Genetics