Serotonin transporter gene and inhibition of conflicting emotional information

Ai Koizumi, Norimichi Kitagawa, Miho Kitamura, Hirohito M. Kondo, Takao Sato, Makio Kashino

研究成果: Article

12 引用 (Scopus)

抄録

Genetic variation of the serotonin-transporter-linked promoter region has been reported to be associated with susceptibility to mood disorders. However, little is known about the behavioral characteristics that mediate this genetic variation and susceptibility to depression. We examined whether the serotonin-transporter genotype modulates inhibition of facial expressions and emotional words in the emotional 'face-word' Stroop task. Although negative word distractors interfered with the valence identification of positive faces among carriers of two short alleles, positive word distractors interfered with that of negative faces among carriers of one or two long alleles. We discuss a possible role of the reduced inhibitory control over semantic negative information in carriers of two short alleles in the risk of developing depressive mental state.

元の言語English
ページ(範囲)422-426
ページ数5
ジャーナルNeuroReport
21
発行部数6
DOI
出版物ステータスPublished - 2010
外部発表Yes

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Serotonin Plasma Membrane Transport Proteins
Alleles
Genes
Facial Expression
Genetic Predisposition to Disease
Mood Disorders
Semantics
Genetic Promoter Regions
Genotype
Depression
Inhibition (Psychology)

ASJC Scopus subject areas

  • Neuroscience(all)

これを引用

Serotonin transporter gene and inhibition of conflicting emotional information. / Koizumi, Ai; Kitagawa, Norimichi; Kitamura, Miho; Kondo, Hirohito M.; Sato, Takao; Kashino, Makio.

:: NeuroReport, 巻 21, 番号 6, 2010, p. 422-426.

研究成果: Article

Koizumi, A, Kitagawa, N, Kitamura, M, Kondo, HM, Sato, T & Kashino, M 2010, 'Serotonin transporter gene and inhibition of conflicting emotional information', NeuroReport, 巻. 21, 番号 6, pp. 422-426. https://doi.org/10.1097/WNR.0b013e32833833f0
Koizumi, Ai ; Kitagawa, Norimichi ; Kitamura, Miho ; Kondo, Hirohito M. ; Sato, Takao ; Kashino, Makio. / Serotonin transporter gene and inhibition of conflicting emotional information. :: NeuroReport. 2010 ; 巻 21, 番号 6. pp. 422-426.
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