抄録
Eduline (la), graveoline (1b), and 6-methoxy-2-(4-methoxyphenyl)-1-methylquinolone (1c) were synthesized by iridium-catalyzed three-component coupling reaction. Reaction of an aniline, an aromatic aldehyde, and acetaldehyde gave the corresponding substituted quinoline. Using 1,1-dimethoxyethane instead of acetaldehyde, the three component coupling reactions were also carried out to give the quinolines in higher yields. N-Methylation of the quinolines with methyl trifrate followed by oxidation with potassium ferricianate gave the quinolones.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 497-504 |
| ページ数 | 8 |
| ジャーナル | Heterocycles |
| 巻 | 69 |
| 号 | 1 |
| 出版ステータス | Published - 2006 12 1 |
ASJC Scopus subject areas
- Organic Chemistry