Solubilization of dipropofol, an antibacterial agent, using saccharide and ascorbic acid

Masahiro Ogata, K. Oka, Masako Seki, Midori Hoshi, Hirokatsu Takatsu, Tadahiko Mashino, Shiro Urano, Toyoshige Endo

研究成果: Article

3 引用 (Scopus)

抜粋

Dipropofol has a strong antibacterial activity against Gram-positive bacteria. However, it lacked the solubility in water and this property was supposed to limit its efficacy. We tried to improve the solubility and found a new solubilization method of dipropofol in water by the addition of a monosaccharide or ascorbic acid.

元の言語English
ページ(範囲)1565-1568
ページ数4
ジャーナルBiological and Pharmaceutical Bulletin
30
発行部数8
DOI
出版物ステータスPublished - 2007 8
外部発表Yes

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology, Toxicology and Pharmaceutics(all)

フィンガープリント Solubilization of dipropofol, an antibacterial agent, using saccharide and ascorbic acid' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用

    Ogata, M., Oka, K., Seki, M., Hoshi, M., Takatsu, H., Mashino, T., Urano, S., & Endo, T. (2007). Solubilization of dipropofol, an antibacterial agent, using saccharide and ascorbic acid. Biological and Pharmaceutical Bulletin, 30(8), 1565-1568. https://doi.org/10.1248/bpb.30.1565