Static magnetic field stimulation applied over the cervical spinal cord can decrease corticospinal excitability in finger muscle

Kento Nakagawa*, Kimitaka Nakazawa

*この研究の対応する著者

研究成果: Article査読

6 被引用数 (Scopus)

抄録

Objective: Transcranial static magnetic field stimulation has recently been demonstrated to modulate cortical excitability. In the present study, we investigated the effect of transspinal static magnetic field stimulation (tsSMS) on excitability of the corticospinal tract. Methods: A compact magnet for tsSMS (0.45 Tesla) or a stainless steel cylinder for sham stimulation was positioned over the neck (C8 level) of 24 able-bodied subjects for 15 min. Using 120% of the resting motor threshold transcranial magnetic stimulation intensity, motor evoked potentials (MEPs) were measured from the first digital interosseous muscle before, during, and after the tsSMS or sham intervention. Results: Compared with baseline MEP amplitudes were decreased during tsSMS, but not during sham stimulation. Additionally, during the intervention, MEP amplitudes were lower with tsSMS than sham stimulation, although these effects did not last after the intervention ceased. Conclusions: The results suggest that static magnetic field stimulation of the spinal cord by a compact magnet can reduce the excitability of the corticospinal tract. Significance: Transspinal static magnetic field stimulation may be a new non-invasive neuromodulatory tool for spinal cord stimulation. Its suppressive effect may be applied to patients who have pathological hyperexcitability of the spinal neural network.

本文言語English
ページ(範囲)49-53
ページ数5
ジャーナルClinical Neurophysiology Practice
3
DOI
出版ステータスPublished - 2018
外部発表はい

ASJC Scopus subject areas

  • 神経学
  • 臨床神経学
  • 生理学(医学)

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