@article{99ac997bcde8485ca888675fc2f7191d,
title = "Stereoselective construction of a quaternary carbon substituted with multifunctional groups: Application to the concise synthesis of (+)-ethosuximide",
abstract = "Synthetically useful β,γ-unsaturated carbonyl compounds having a quaternary carbon at the α-position were prepared with high stereoselectivity by the reaction of a dienolate anion derived from α,β-unsaturated imide having a chiral auxiliary and electrophiles (ethyl acetate and allyl iodide as the C2 and C3 unit, respectively). This method was applied to a short asymmetric synthesis of (+)-ethosuximide.",
author = "Tomoaki Abe and Tatsuo Suzuki and Kazuhiko Sekiguchi and Seijiro Hosokawa and Susumu Kobayashi",
note = "Funding Information: This work was supported in part by the Fujisawa Foundation (S.H.) and Grant-in-Aids for Scientific Research from the Ministry of Education, Culture, Sports, and, Science and Technology, Japan.",
year = "2003",
month = dec,
day = "22",
doi = "10.1016/j.tetlet.2003.10.081",
language = "English",
volume = "44",
pages = "9303--9305",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "52",
}