抜粋
Synthetically useful β,γ-unsaturated carbonyl compounds having a quaternary carbon at the α-position were prepared with high stereoselectivity by the reaction of a dienolate anion derived from α,β-unsaturated imide having a chiral auxiliary and electrophiles (ethyl acetate and allyl iodide as the C2 and C3 unit, respectively). This method was applied to a short asymmetric synthesis of (+)-ethosuximide.
| 元の言語 | English |
|---|---|
| ページ（範囲） | 9303-9305 |
| ページ数 | 3 |
| ジャーナル | Tetrahedron Letters |
| 巻 | 44 |
| 発行部数 | 52 |
| DOI | |
| 出版物ステータス | Published - 2003 12 22 |
| 外部発表 | Yes |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry
フィンガープリント Stereoselective construction of a quaternary carbon substituted with multifunctional groups: Application to the concise synthesis of (+)-ethosuximide' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。
これを引用
Abe, T., Suzuki, T., Sekiguchi, K., Hosokawa, S., & Kobayashi, S. (2003). Stereoselective construction of a quaternary carbon substituted with multifunctional groups: Application to the concise synthesis of (+)-ethosuximide. Tetrahedron Letters, 44(52), 9303-9305. https://doi.org/10.1016/j.tetlet.2003.10.081