抄録
The highly stereoselective total synthesis of nemorosone via a new approach to the bicyclo[3.3.1]nonane-2,4,9-trione core which features intramolecular cyclopropanation of an α-diazo ketone, stereoselective alkylation at the C8 position, and regioselective ring-opening of cyclopropane is described. The total synthesis of nemorosone includes chemo- and stereoselective hydrogenation directed by the internal alkene.
本文言語 | English |
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ページ(範囲) | 5098-5107 |
ページ数 | 10 |
ジャーナル | Journal of Organic Chemistry |
巻 | 77 |
号 | 11 |
DOI | |
出版ステータス | Published - 2012 6月 1 |
ASJC Scopus subject areas
- 有機化学