Stereoselective total synthesis of nemorosone

Masahiro Uwamori; Aya Saito; Masahisa Nakada

doi:10.1021/jo300646j

Stereoselective total synthesis of nemorosone

Masahiro Uwamori, Aya Saito, Masahisa Nakada^*

^*この研究の対応する著者

先進理工学部

研究成果: Article › 査読

51 被引用数 (Scopus)

抄録

The highly stereoselective total synthesis of nemorosone via a new approach to the bicyclo[3.3.1]nonane-2,4,9-trione core which features intramolecular cyclopropanation of an α-diazo ketone, stereoselective alkylation at the C8 position, and regioselective ring-opening of cyclopropane is described. The total synthesis of nemorosone includes chemo- and stereoselective hydrogenation directed by the internal alkene.

本文言語	English
ページ（範囲）	5098-5107
ページ数	10
ジャーナル	Journal of Organic Chemistry
巻	77
号	11
DOI	https://doi.org/10.1021/jo300646j
出版ステータス	Published - 2012 6月 1

ASJC Scopus subject areas

有機化学

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10.1021/jo300646j

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Stereoselective total synthesis of nemorosone

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