Stochastic determinism underlying life: Systematic theory for assisting the synthesis of artificial cells and new medicines

Ken Naitoh*

*この研究の対応する著者

研究成果: Article査読

23 被引用数 (Scopus)

抄録

The frequencies of purines and pyrimidines in double-strand DNA are in a symmetric ratio of 1: 1, while the asymmetric density ratios of purines and pyrimidines in RNA and artificial ribozymes are between 1: 1 and approximately 1: 1.5. The frequency ratio in DNA is deterministic, while that in RNA is fairly stochastic. Symbiotic fusion of deterministic symmetry and stochastic asymmetry, which can be seen at the molecular, cell and whole-body levels, is a key concept for understanding the self-organizing processes in living organisms. The left-right symmetric distribution of arms and legs is observed in outward appearance, although the inner body, including the heart and the liver, is asymmetric. A minimum hypercycle of four cycles at the origin of life is also in the symbiotic fusion of symmetry and asymmetry. The inevitability of deterministic symmetry and stochastic asymmetry underlying life is systematically revealed on the basis of physics as the weft and molecular biology as the warp.

本文言語English
ページ(範囲)10-17
ページ数8
ジャーナルArtificial Life and Robotics
13
1
DOI
出版ステータスPublished - 2008 12月 1

ASJC Scopus subject areas

  • 生化学、遺伝学、分子生物学(全般)
  • 人工知能

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