Stochasticity of the step size in the force generating process due to a single myosin molecule

Yuki Kagawa, Yoshimi Tsuchiya

研究成果: Article査読

2 被引用数 (Scopus)

抄録

We formulate a motional model on the basis of an experimental optical trapping system which reveals the single molecular events of the force generation due to actin and myosin, and we discuss the origin of the dispersion of the displacements of the beads bound to the actin filament. In some experimental data sets, this dispersion is larger than that presumed from the model under the condition that the thermal agitation is the only source of the fluctuation. Thus, other fluctuating elements besides that due to thermal agitation are supposed to cause the dispersion. A possible fluctuating element is the step size itself. We discuss this possibility and estimate the fluctuation in step size using two reported experimental data sets.

本文言語English
ページ(範囲)407-419
ページ数13
ジャーナルBulletin of Mathematical Biology
64
2
DOI
出版ステータスPublished - 2002 3

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

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