Structures of genes encoding TATA box-binding proteins from trimeresurus gramineus and t. flavoviridis snakes

Kin ichi Nakashima, Ikuo Nobuhisa, Masanobu Deshimaru, Tomohisa Ogawa, Yasuyuki Shimohigashi, Yasuyuki Fukumaki, Masahira Hattori, Yoshiyuki Sakaki, Shosaku Hattori, Motonori Ohno*

*この研究の対応する著者

研究成果: Article査読

27 被引用数 (Scopus)

抄録

A cDNA encoding the Trimeresurus gramineus (Tg; green habu snake) TATA-box-binding protein (TgTBP) was cloned and sequenced. The cDNA encodes a 33-kDa protein with an extensive sequence similarity to those derived from other organisms, except for the N-terminal domain. Genes encoding TgTBP and Trimeresurus flavoviridis (Tf; habu snake) TBP (TgTBP) were isolated using a TgTBP cDNA and their nt sequences were determined. They are the first TBP genes entirely sequenced in higher animals. Both genes span over 15 kb and are constructed from eight exons and seven introns. Comparison of the loci of introns on the aligned amino-acid sequences of TBP from six organisms (Tg, Tf, mouse, Arabidopsis thaliana, Schizosaccharomyces pombe and Acanthamoeba castellanii) indicated that there are three highly conserved loci in the C-terminal domain.

本文言語English
ページ(範囲)209-213
ページ数5
ジャーナルGene
152
2
DOI
出版ステータスPublished - 1995 1 23
外部発表はい

ASJC Scopus subject areas

  • 遺伝学

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