Sustained release control via photo-cross-linking of polyelectrolyte layer-by-layer hollow capsules

Mi Kyoung Park, Suxiang Deng, Rigoberto C. Advincula

研究成果: Article

63 引用 (Scopus)

抜粋

We describe the formation and permeability of polyelectrolyte multilayer hollow-shell capsules by photo-cross-linking and controlled-release (fluorescence) studies. The hollow shells were prepared by alternate layer-by-layer (LbL) adsorption of photo-cross-linkable benzophenone modified poly(allylamme hydrochloride) and poly(sodium 4-styrenesulfonate) on polystyrene particles, followed by removing the core with tetrahydrofuran. Zeta potential measurements, fourier transform infrared spectroscopy, and transmission electron microscopy were used to verify the LbL process integrity. A model drug, rhodamine B (RB), was successfully loaded into the polyelectrolyte hollow capsules. The release kinetics of RB was investigated using fluorescence spectroscopy. The permeability of RB through the hollow shells was effectively controlled based on UV irradiation time. It was shown that the release of RB molecules can be controlled by the degree of cross-linking induced in the multilayer.

元の言語English
ページ(範囲)5272-5277
ページ数6
ジャーナルLangmuir
21
発行部数12
DOI
出版物ステータスPublished - 2005 6 7
外部発表Yes

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Spectroscopy
  • Electrochemistry

フィンガープリント Sustained release control via photo-cross-linking of polyelectrolyte layer-by-layer hollow capsules' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用