抄録
We describe the formation and permeability of polyelectrolyte multilayer hollow-shell capsules by photo-cross-linking and controlled-release (fluorescence) studies. The hollow shells were prepared by alternate layer-by-layer (LbL) adsorption of photo-cross-linkable benzophenone modified poly(allylamme hydrochloride) and poly(sodium 4-styrenesulfonate) on polystyrene particles, followed by removing the core with tetrahydrofuran. Zeta potential measurements, fourier transform infrared spectroscopy, and transmission electron microscopy were used to verify the LbL process integrity. A model drug, rhodamine B (RB), was successfully loaded into the polyelectrolyte hollow capsules. The release kinetics of RB was investigated using fluorescence spectroscopy. The permeability of RB through the hollow shells was effectively controlled based on UV irradiation time. It was shown that the release of RB molecules can be controlled by the degree of cross-linking induced in the multilayer.
| 元の言語 | English |
|---|---|
| ページ（範囲） | 5272-5277 |
| ページ数 | 6 |
| ジャーナル | Langmuir |
| 巻 | 21 |
| 発行部数 | 12 |
| DOI | |
| 出版物ステータス | Published - 2005 6 7 |
| 外部発表 | Yes |
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ASJC Scopus subject areas
- Materials Science(all)
- Condensed Matter Physics
- Surfaces and Interfaces
- Spectroscopy
- Electrochemistry
これを引用
Sustained release control via photo-cross-linking of polyelectrolyte layer-by-layer hollow capsules. / Park, Mi Kyoung; Deng, Suxiang; Advincula, Rigoberto C.
：: Langmuir, 巻 21, 番号 12, 07.06.2005, p. 5272-5277.研究成果: Article
}
TY - JOUR
T1 - Sustained release control via photo-cross-linking of polyelectrolyte layer-by-layer hollow capsules
AU - Park, Mi Kyoung
AU - Deng, Suxiang
AU - Advincula, Rigoberto C.
PY - 2005/6/7
Y1 - 2005/6/7
N2 - We describe the formation and permeability of polyelectrolyte multilayer hollow-shell capsules by photo-cross-linking and controlled-release (fluorescence) studies. The hollow shells were prepared by alternate layer-by-layer (LbL) adsorption of photo-cross-linkable benzophenone modified poly(allylamme hydrochloride) and poly(sodium 4-styrenesulfonate) on polystyrene particles, followed by removing the core with tetrahydrofuran. Zeta potential measurements, fourier transform infrared spectroscopy, and transmission electron microscopy were used to verify the LbL process integrity. A model drug, rhodamine B (RB), was successfully loaded into the polyelectrolyte hollow capsules. The release kinetics of RB was investigated using fluorescence spectroscopy. The permeability of RB through the hollow shells was effectively controlled based on UV irradiation time. It was shown that the release of RB molecules can be controlled by the degree of cross-linking induced in the multilayer.
AB - We describe the formation and permeability of polyelectrolyte multilayer hollow-shell capsules by photo-cross-linking and controlled-release (fluorescence) studies. The hollow shells were prepared by alternate layer-by-layer (LbL) adsorption of photo-cross-linkable benzophenone modified poly(allylamme hydrochloride) and poly(sodium 4-styrenesulfonate) on polystyrene particles, followed by removing the core with tetrahydrofuran. Zeta potential measurements, fourier transform infrared spectroscopy, and transmission electron microscopy were used to verify the LbL process integrity. A model drug, rhodamine B (RB), was successfully loaded into the polyelectrolyte hollow capsules. The release kinetics of RB was investigated using fluorescence spectroscopy. The permeability of RB through the hollow shells was effectively controlled based on UV irradiation time. It was shown that the release of RB molecules can be controlled by the degree of cross-linking induced in the multilayer.
UR - http://www.scopus.com/inward/record.url?scp=20744440823&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=20744440823&partnerID=8YFLogxK
U2 - 10.1021/la047008x
DO - 10.1021/la047008x
M3 - Article
VL - 21
SP - 5272
EP - 5277
JO - Langmuir
JF - Langmuir
SN - 0743-7463
IS - 12
ER -