Synchronized stereocontrol of planar chirality by crystallization-induced asymmetric transformation

Nobuhiro Kanomata, Gou Mishima, Jun Onozato

研究成果: Article査読

18 被引用数 (Scopus)

抄録

Synchronized stereocontrol of two planar-chiral units was accomplished by using crystallization-induced asymmetric transformation (CIAT) of cyclophane-type bridged bisnicotinate derivatives 5b and 7. After screening various linkers, (S)-2-amino-1-butanol and (S)-tert-leucinol were found to be the most effective for CIAT of the corresponding bridged bisnicotinate 5b and 7, respectively, whose diastereomeric ratio finally reached 97% and 88%, respectively.

本文言語English
ページ(範囲)409-412
ページ数4
ジャーナルTetrahedron Letters
50
4
DOI
出版ステータスPublished - 2009 1 28

ASJC Scopus subject areas

  • 生化学
  • 創薬
  • 有機化学

フィンガープリント

「Synchronized stereocontrol of planar chirality by crystallization-induced asymmetric transformation」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル