Synthesis and structure formation in dilute aqueous solution of a chitosan-DNA hybrid

Ilyès Safir, Kien Xuan Ngo, Jancy Nixon Abraham, Majid Ghahraman Afshar, Ewa Pavlova, Corinne Nardin*

*この研究の対応する著者

研究成果: Article査読

9 被引用数 (Scopus)

抄録

In the following is described the combination of straight biochemical and organic routes to graft nucleotide sequences to a chitosan backbone. The resulting chitosan-g-ssDNA hybrid self-assembles into submicrometer size structures in dilute aqueous solution as assessed by atomic force and electron microscopy imaging. The hypothesis of self-assembly driven by chemical incompatibility between the amphiphilic chitosan and nucleic acid grafts is supported further by stability of the self-assembly against ionic strength and pH variations.

本文言語English
ページ(範囲)29-36
ページ数8
ジャーナルPolymer (United Kingdom)
79
DOI
出版ステータスPublished - 2015 11 19
外部発表はい

ASJC Scopus subject areas

  • ポリマーおよびプラスチック
  • 有機化学

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