Synthesis of a heptaarylisoquinoline: Unusual disconnection for constructing isoquinoline frameworks

Takashi Asako, Shin Suzuki, Kenichiro Itami, Kei Muto, Junichiro Yamaguchi

研究成果: Article

抜粋

In a novel disconnection of isoquinoline ring synthesis at the C7C8/C4aC8a bonds, these bonds can be formed by a [4+2] cycloaddition between thiophene S,S-dioxide and alkynes. With a subsequent CH arylation of the resulting hexaarylisoquinoline at the C3 position, the synthesis of a fully substituted isoquinoline has been achieved.

元の言語English
ページ(範囲)968-970
ページ数3
ジャーナルChemistry Letters
47
発行部数8
DOI
出版物ステータスPublished - 2018 1 1

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ASJC Scopus subject areas

  • Chemistry(all)

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