Synthesis of alkylsulfonio-porphyrin complexes and its anti-cancer and anti-oxidant properties

Masayasu Komuro, Ryota Awa, Yuji Ito, Aritomo Yamaguchi, Kenichi Oyaizu, Makoto Yuasa

研究成果: Paper

抜粋

In living body, oxygen (O2) generates reactives oxygen species (ROS) such as superoxide anion radical (O2- ·). Living body has superoxide dismutase (SOD) enzyme for elimination of ROS. However, decrese of activity of SOD causes inflammation, cancer, and other deseases. In this study, we synthesized metalloporphyrins as anti-oxidant and anti-cancer drug. Novel alkylsulfonioporphyrin complexes were synthesized. It was revealed that they were effective as anti-oxidant and as anti-cancer agents, by stopped-flow method and cell viability tests, respectively.

元の言語English
ページ数1
出版物ステータスPublished - 2005 12 1
外部発表Yes
イベント54th SPSJ Annual Meeting 2005 - Yokohama, Japan
継続期間: 2005 5 252005 5 27

Conference

Conference54th SPSJ Annual Meeting 2005
Japan
Yokohama
期間05/5/2505/5/27

ASJC Scopus subject areas

  • Engineering(all)

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  • これを引用

    Komuro, M., Awa, R., Ito, Y., Yamaguchi, A., Oyaizu, K., & Yuasa, M. (2005). Synthesis of alkylsulfonio-porphyrin complexes and its anti-cancer and anti-oxidant properties. 論文発表場所 54th SPSJ Annual Meeting 2005, Yokohama, Japan.