Synthesis of alkylsulfonio-porphyrin complexes and its anti-cancer and anti-oxidant properties

Masayasu Komuro, Ryota Awa, Yuji Ito, Aritomo Yamaguchi, Kenichi Oyaizu, Makoto Yuasa

研究成果: Paper査読

抄録

In living body, oxygen (O2) generates reactives oxygen species (ROS) such as superoxide anion radical (O2- ·). Living body has superoxide dismutase (SOD) enzyme for elimination of ROS. However, decrese of activity of SOD causes inflammation, cancer, and other deseases. In this study, we synthesized metalloporphyrins as anti-oxidant and anti-cancer drug. Novel alkylsulfonioporphyrin complexes were synthesized. It was revealed that they were effective as anti-oxidant and as anti-cancer agents, by stopped-flow method and cell viability tests, respectively.

本文言語English
ページ数1
出版ステータスPublished - 2005 12 1
外部発表はい
イベント54th SPSJ Annual Meeting 2005 - Yokohama, Japan
継続期間: 2005 5 252005 5 27

Conference

Conference54th SPSJ Annual Meeting 2005
CountryJapan
CityYokohama
Period05/5/2505/5/27

ASJC Scopus subject areas

  • Engineering(all)

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